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Profhilo® is one of the latest treatments for bio-remodelling using hyaluronic acid (HA) which stimulates the production of natural collagen and elasticity in the skin. Unlike traditional dermal fillers, Profhilo® doesn’t volumise but instead stimulates the laying-down of new collagen and elastin in the superficial layers, just under the surface of the skin.

What’s so great about the Skin Institute’s multi-disciplinary approach is that we can offer patients the whole package – from education, to treatment, to follow up care.

Dr Shona Dalzell
Appearance Medicine, Dermatology Associate, Skin Cancer, Veins
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Book a cosmetic consultation with one of our Appearance Medicine Nurses.

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Book a cosmetic consultation

Book a cosmetic consultation with one of our Appearance Medicine Nurses.

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What is Profhilo®?

Profhilo® is a unique injectable made of a high concentration of a carbohydrate called hyaluron that is naturally present in the skin but declines with age. It promotes skin hydration and collagen formation. Profhilo® has a unique formulation which is free of additives. Its’ consistency is like runny honey, as such that allows it to evenly spread through the skin tissues and underlying structures forming a hydrating layer as well as stimulating cell production including collagen and elastin.

What is it used for?

Unlike other anti-ageing injectables, Profhilo® uses HA which is used to treat skin laxity and to help remodel ageing, sagging and crepey skin. It hydrates and firms the skin and is shown to have a stimulatory effect on the cells producing collagen and elastin to help tighten, lift the skin and improve skin quality to give it a more youthful look. The results of Profhilo® treatments can last up to 6-9 months, however, this may vary by patient and depends on skin type and age. Treatment stimulates new collagen and elastin cells, and improves the appearance of fine lines and wrinkles.

What does the treatment involve?

The treatment involves placing the product under the skin using a fine needle at points which are chosen to ensure safety and maximise the lifting action of the product. Profhilo® spreads evenly throughout the surrounding tissues to hydrate and stimulate the collagen and elastin production. For a result, you are required to have 2 treatments one month apart. After a 6 to 9 month period or when you begin to see the treatment’s effects wearing away, then you can top up treatments if you wish to continue. The Profhilo® treatment can work independently as a treatment on its own or in combination with other cosmetic treatments.

Who should not have Profhilo®?

Those previously allergic to hyaluronan; anaphylaxis reaction to bee-stings, pregnant or breast-feeding; with permanent fillers or facial implants; unwell with a cold, sinusitis or facial infection; prior keloid scarring; planned dental treatment in a month or flying overseas in under four days. It is best avoided if you have had a recent vaccination. Caution is needed in those with autoimmune disorders.

What about combining with other cosmetic treatments?

You can use Profhilo® with other cosmetic treatments, but we advise no botulinum toxin for two weeks prior. No microdermabrasion, chemical peel, IPL for 1–2 weeks pre or post treatment. Avoid fractional resurfacing 4 weeks pre and post Profhilo® treatment.

What are the rare side effects?

This treatment is relatively unproblematic and well tolerated. Allergy is unlikely, as Profhilo® is free from synthetic chemicals, but it is still a possibility and may result in swelling redness or hard lumps. This is treated by dissolving the Profhilo with an enzyme. As the skin barrier is breached during placement, there is a rare risk of infection which may require antibiotics. It is extremely unlikely that vascular occlusion will occur due to the placement sites of the product. However, it remains a possibility that Profhilo® may inadvertently enter a vessel which can cause skin damage and scarring unless treated by dissolving enzyme which removes all filler. With other fillers, there have been extremely rare reports of blindness or stroke, with treatment of the nose and between the eyes carrying a higher risk and this remains a possible risk with this treatment.


Profhilo®, containing low & high molecular weight hyaluronic acid, is a Class lll medical device for the treatment of the face and body for contours, redefinition and laxity remodelling where skin laxity is a problem. Profhilo® has risks and benefits. Do not use with treatments such as laser resurfacing or medium deep skin-peeling. Do not inject into inflamed areas or intravenously or intramuscularly. Possible side effects: pain and swelling at injection site.

Individual results may vary. This medical device must be administered by a healthcare professional. Skin Institute Level 1, 29 Northcroft Street, Takapuna, Auckland 0622.

Why Skin Institute?

Feeling confident and looking the best you can are things we all aim for. Skin Institute has over twenty years of experience in skincare, and we pride ourselves on keeping at the forefront of developments in appearance medicine. Our expert teams are helping Kiwis across the country show the world their best face – and you could be one of them.

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Book a cosmetic consultation

Book a cosmetic consultation with one of our Appearance Medicine Nurses.